Application of norepinephrine in septic shock
- VernacularTitle:去甲肾上腺素在脓毒症休克中的应用进展
- Author:
Zhenzhong DENG
;
Yunzhao ZHAO
- Publication Type:Journal Article
- Keywords:
Septic shock;
Microcirculation resuscitation;
Norepinephrine
- From:
Journal of Medical Postgraduates
2003;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
The inappropriate use of norepinephrine(NE) in hypovolemic shock may be deleterious with potentially adverse vasoconstriction and subsequent hypoperfusion.Dramatically,based on the sufficient fluid resuscitation,high doses of NE administered rather increases the blood flow and oxygen delivery during sepsis.The mechanism may contribute to the reverse of vascular hyporesponsiveness and realization of microcirculation resuscitation.However,the optimal time,dosage and combination of NE with other vasoactive agents still necessarites further investigation.
