Significance of unbalance of cell proliferation and apoptosis in aspergillus
- VernacularTitle:细胞增殖和凋亡失调在肺曲菌病发病中的意义
- Author:
Lingling ZHOU
;
Zongmin WANG
;
Hui XIA
;
Zhiguang ZHAO
- Publication Type:Journal Article
- Keywords:
KI-67;
BCL-2;
BAX;
aspergillus;
immunohistochemistry
- From:
Basic & Clinical Medicine
2006;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the expression of cell proliferation and apoptosis in congenital pulmonary cyst and to investigate their effect in the development of aspergillus.Methods Immunohistochemical method was used to detect the expression of KI-67、BCL-2 and BAX in normal lung tissue from 10 adult(control group 1,CG1),relative normal lung tissue around the aspergillus from 20 aspergillus cases(control group 2,CG2)and abnormal lung tissue from 20 aspergillus cases.Results The expressions of KI-67,BAX and the ratio of BAX/BCL-2 in the bronchial epithelium of aspergillus were significantly higher than those in two control groups(P
