Drug Resistance of Pseudomonas aeruginosa to Ceftazidime and Its Risk Factors
- VernacularTitle:铜绿假单胞菌对头孢他啶耐药率及其影响因素
- Author:
Shaojun ZHANG
;
Jiayou LUO
- Publication Type:Journal Article
- Keywords:
Pseudomonas aeruginosa;
Resistance;
Risk factors
- From:
Chinese Journal of Nosocomiology
2006;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE To explore the drug resistance rate and risk factor of Pseudomonas aeruginosa against ceftazidime in a certain hospital,and provide scientific basis for preventing the P.aeruginosa infections.METHODS A total of 109 P.aeruginosa strains,which were isolated from sputum cultures in patients in a certain hospital in 2005,were identified with VITEK GNI+ automation system.The possible risk factors and underlying diseases were investigated by reviewing patients′ medical records.Multiple Logistic regression models were used for statistical analyses by SPSS software(13.0).RESULTS The resistant ratios against ceftazidime was 38.5%.P.aeruginosa resistant ratios in ICU and the neurosurgery ward were 78.57% and 54.84%,respectively,and higher than others.Treatment days before infection in hospital(over two days),staying at the ICU or neurosurgery ward,using breathing machine,were associated with the sensitivity to ceftazidime for P.aeruginosa.CONCLUSIONS In order to prevent and reduce the drug resistant ratios for P.aeruginosa,we should pay more attention to the patients admitted in ICU and neurosurgery wards.Risk factors,such as treatment days in hospital,living in different wards and using breathing machine,were associated with the resistant ratios for P.aeruginosa against ceftazidime.
