Blood Pressure Weighted Standard Deviation and the Target Organ Damage in the Very Elderly with Hypertension
- VernacularTitle:高龄老年原发性高血压患者血压24h加权标准差与靶器官损害的相关性
- Author:
Xin ZHAO
;
Yaping YI
;
Yi QU
;
Ningyuan FANG
- Publication Type:Journal Article
- Keywords:
Hypertension;
The very elderly;
Ambulatory blood pressure monitoring;
Arterial blood pressure variability;
Left ventricular mass;
Carotid intima-media thickness
- From:
Chinese Journal of Hypertension
2007;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Background Greater variability in blood pressure and the disappearance of circadian rhythm are frequently found in the very elderly with hypertension.Blood pressure variability may be closely related to the target organ damages.Objective To assess the relationship between nocturnal blood pressure fall(NBPF)and 24 h blood pressure variability(BPV)by using BP weighted standard deviation as a new index for computing 24 h BPV,and to verify the clinical value of this new marker in the very elderly with hypertension.Methods We analysed retrospectively 1441 ambulatory blood pressure(BP)recordings,and computed:①the standard deviation(SD)of 24 h BP directly from all individual readings;②weighted mean value of daytime and night-time SD(wSD);③the magnitude of nocturnal BP fall(NBPF).Left ventricular mass(n=345)and carotid intima-media thickness(n=216)were determined by echocardiography.Results The 24 h SD of BP was significantly greater than the 24 h wSD(P
