Isolation,purification and structure determination of antifungal antibiotic FW03-1149 produced by marine Micromonospora sp.FIM03-1149
- VernacularTitle:海洋小单孢菌FIM03-1149产生的抗真菌抗生素FW03-1149的分离鉴别
- Author:
Yilei NIE
;
Ru LIN
;
Yang XIE
;
Hong JIANG
- Publication Type:Journal Article
- Keywords:
Micromonospora;
antifungal antibiotics;
neorustmicin
- From:
Chinese Journal of Marine Drugs
1994;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the antifungal metabolites from marine microorganism FIM03-1149.Methods The producing strain was identified by taxonomical studies.The antifungal compound FW03-1149 was extracted by organic solvents and purified by silica gel column and preparative HPLC from the culture broth of FIM 03-1149.The structure of FW03-1149 was determined by MS data analysis and physico-chemical properties.Results and Conclusion The producing strain was named as Micromonospora sp.FIM03-1149.Compound FW03-1149 was determined to be neorustmicin,showed strong antifungal activities.
