Esophagus memory Ni-Ti alloy stent for malignant stenosis, esophagus and anastomotic stoma fistula in 60 cases
- VernacularTitle:食管记忆金属支架置入食管狭窄及食管、吻合口瘘60例
- Author:
Lan JIANG
- Publication Type:Journal Article
- From:
Chinese Journal of Tissue Engineering Research
2007;0(09):-
- CountryChina
- Language:Chinese
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Abstract:
Sixty patients with malignant stenosis, esophagus and anastomotic stoma fistula were selected from Jiangsu General Hospital of Armed Police Forces between January 1995 and June 2008, including 46 males and 14 females, aged 36-77 years. Following pathologic diagnosis, 50 patients had squamous cell carcinoma, 8 had adenocarcinoma, and 2 had adeno-squamous carcinoma. Of 60 patients, 33 had esophageal carcinoma stenosis and esophagus-gastric cardia carcinoma stenosis, 20 had esophageal carcinoma stenosis combined with fistula, 7 had esophageal-stomach anastomosis combined with thoracic cavity fistula; in addition, there were 22 cases of first onset of fistula and 5 of multiple fistula. All patients were treated by esophagus memory Ni-Ti alloy coated stent implantation. Of 58 patients with successful implantation, 21 developed stent blockage due to dysphagia, and were alleviated after foreign body removal; 3 developed stent dislocation (removal and re-implanted); 7 developed restenosis due to tumor tissue ingrowth 3 months after implantation. Of 5 patients with multiple fistula, 3 were re-implanted to form invagination of 2 stents, which succeeded in blocking the fistula. Of 33 patients with esophageal carcinoma stenosis and esophagus-gastric cardia carcinoma stenosis, 26 underwent radiotherapy with or without chemotherapy (mean survival time: 24 months). Twenty patients with esophageal carcinoma stenosis combined with fistula survived for 6 months averagely. Seven patients with esophageal-stomach anastomosis combined with thoracic cavity fistula survived for 3 months averagely. Of 60 patients, 42 felt retrosternal pain, and 2 patients’ stents were extracted due to severe pain; 20 patients developed esophageal reflux. No bleeding, perforation or septicemia occurred. The results indicate that memory Ni-Ti alloy stent is effective in treating malignant stenosis, esophagus and anastomotic stoma fistula, showing good biocompatibility.
