Intravascular stent and rapid vascular endothelialization following stent implantation
- VernacularTitle:心血管支架与支架置入后的血管快速内皮化
- Author:
Wei XING
- Publication Type:Journal Article
- From:
Chinese Journal of Tissue Engineering Research
2007;0(09):-
- CountryChina
- Language:Chinese
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Abstract:
Intravascular stent has been widely used in clinic to treat cardiovascular diseases, but the complications gradually present. Vascular endothelialization following stent implantation is a key factor that influences the biocompatibility of material and human body. After stent implantation, vascular endothelium function is abnormal, inducing endodermis shedding, platelet aggregation, inflammatory reactions, vascular smooth muscle cell proliferation and migration, and excellular matrix formation. These pathological reactions cause in-stent restenosis. So repair and functional changes of vascular endothelial cells play an important role in in-stent restenosis. To deeply understand the vascular endothelialization following implantation of various stents, this paper discussed rapid vascular endothelialization by retrieving articles so as to search a method to solve this problem.