Resistance and Molecular Epidemiology of Pseudomonas aeruginosa Isolated from ICU
- VernacularTitle:重症监护病房分离铜绿假单胞菌的耐药性及分子流行病学检测
- Author:
Zhongxin WANG
;
Yanyan WEI
;
Zizhong XIONG
- Publication Type:Journal Article
- Keywords:
Pseudomonas aeruginosa;
Antimicrobial agents;
Resistance;
ERIC-PCR
- From:
Chinese Journal of Nosocomiology
1994;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE To investigate the resistance and molecular epidemiology of Pseudomonas aeruginosa isolated from ICU. METHODS Susceptibility of P. aeruginosa isolates to 14 antimicrobial agents were tested by microScan WalkAway-40 system,and Molecular typing was analyzed by enterobacterial repetitive intergenic consensus(ERIC-PCR). RESULTS The lowest resistance rate of P. aeruginosa to the antimicrobial agents was to ceftazidime (27.3%),then to cefepime (45.5%). The highest resistance rate was to cefotaxime (100.0%) and the resistance rate to other antimicrobial agents was more than 60.0%. Patterns of ERIC-PCR were same in 5 strains of P. aeruginosa. CONCLUSIONS P. aeruginosa isolated from ICU is resistant to most of antimicrobial agents and clone spread is found in them. We should enhance detection and surveying of these isolates.
