Clinical Deep Infection of Candida albicansIts Distribution and Resistance
- VernacularTitle:深部感染白色假丝酵母菌的分布及耐药分析
- Author:
Yingjuan SUN
;
Hongmei WANG
;
Qingzeng CHEN
- Publication Type:Journal Article
- Keywords:
Candida albicans;
Antifungal drug;
Infection;
Resistance
- From:
Chinese Journal of Nosocomiology
1994;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE To investigate the distribution and tendency towards drug resistance of Candida albicans which causing clinical deep infection and to supply data to clinical treatment. METHODS The distribution and tendency towards drug resistance of C. albicans isolates from infected patients from Jan 2007 to Dec 2007 were analyzed retrospectively.RESULTS All 1698 strains of Candida were isolated from patients sputum,urine,blood,secretion,etc. From 1075 cases with C. albicans,965(89.8%) strains were isolated from sputum. The resistance rate to nyststin,fluconazole,itraconazole,5-fluorocytosine and amphotericin B were 3.9%,3.6%,2.5%,0.5% and 0,respectively. The factors related to nosocomial C. albicans infection were the use of antibiotics and condition,invasive procedure,physical fitness,age,basic state of patients,etc.CONCLUSIONS The incidence and resistance of C. albicans infection in a hospital have increasing by years. Proper use of antibiotics and immunodepressors,reduction of unnecessary operation,and early diagnosis and treatment are the keys in preventing from systemic C. albicans infection.
