Antiviral Agents in Treating Severe Acute Respiratory Syndrome:A Multi-factorial Analysis
- VernacularTitle:常用抗病毒药物对SARS疗效的多因素分析
- Author:
Dongsheng LIU
;
Juxiang OUYANG
;
Minchao ZOU
;
Yixia LIANG
;
Hongying LIAO
;
Shan LIAO
- Publication Type:Journal Article
- Keywords:
SARS;
Antiviral agents;
Drug evaluation
- From:
Chinese Journal of Nosocomiology
1994;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE To evaluate the effect of antiviral agents in treating of severe acute respiratory syndrome(SARS). METHODS Based on the particular data (including medical history,examiuations and treatments) of 1702 patients of with SARS which were offered by the Health Bureau of Guangdong Province,the inpact factors of death and the course of diseases of SARS were retrospectively analyzed with unifactorial and multifactors statistic analysis methods. RESULTS It did not show any signs that the death rate could be decreased by the six antiviral agents in common use,but vidarabine could help to shorten the course of disease(OR=1.399,P=0.025),while oseltamivir might be prolonged the course of disease(OR=0.708,P=0.000). CONCLUSIONS The data showed that the effect of the six antiviral agents for curing SARS is limited,and a new antiviral treatment for SARS should be explored further.
