Promotion of disequilibrium of cell proliferation and apoptosis of BID as a potential mechanism of IgAN
- VernacularTitle:BID蛋白促细胞凋亡增殖失衡作用与IgA肾病患者病情的关系
- Author:
Lin MA
;
Shuxia FU
;
Lin YANG
;
Jianrong WANG
- Publication Type:Journal Article
- Keywords:
BID protein;
apoptosis;
FN;
IgAN
- From:
Basic & Clinical Medicine
2006;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the expression of BID protein and the relation ship of cell proliferation with apoptosis at different stages of IgAN.Methods The expression of BID protein、PCNA and FN in renal tissue was detected by immunohistochemistry,TUNEL and light microscopy were used to detect apoptotic cells.Results With the progress of IgAN,the expression of BID protein、PCNA、the number of apoptotic cells and FN increased gradually(P
