Application of fluorescence in situ hybridization in the diagnosis of solid tumors
- VernacularTitle:荧光原位杂交技术在实体瘤诊断中的应用
- Author:
Jun DU
;
Xiaojun ZHOU
- Publication Type:Journal Article
- Keywords:
Fluorescence in situ hybridization;
Tumor;
Diagnosis
- From:
Journal of Medical Postgraduates
2004;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
Fluorescence in situ hybridization (FISH) is a non-radioactive technique by use of fluorescently labeled DNA probes in detecting chromosomal alterations in cells. As a new molecular cytological method, it can detect various types of cytogenetic alterations, including deletion, amplification and translocation, as well as improve the accuracy of pathological diagnosis if combined with histomorphology. This review focuses on the application of FISH to the detection of some solid tumors.
