Modified implantation method and spiral CT scan of VX2 liver tumor in rabbit
- VernacularTitle:兔VX2肝癌模型接种方法的改进及螺旋CT观察
- Author:
Bing HAN
;
Yitao DING
;
Dongmei WANG
;
Junlan QIU
;
Weiwei ZHANG
;
Jianbo HAN
;
Wentao KONG
;
Lei YUAN
;
Yudong QIU
- Publication Type:Journal Article
- Keywords:
Liver tumor model;
VX2;
Spiral CT scan;
Implantation of tumor tissue
- From:
Journal of Medical Postgraduates
2004;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To established a modified implanting model of VX2 liver tumor in rabbit on the base of the classic implanting method, and compared the results within the two methods. Methods:30 rabbits with the mean weight of (2.65?0.29)kg were divided randomly into two groups with 15 rabbits each. The rabbits in Group A received classic implantation for induction of the liver tumor model, and Group B were inducted by injecting a piece of tumor tissue into the left anterior lobes of liver. Implanting time of each group was recorded and compared, and spiral CT scan was performed at 8th day, 15th day, 22nd day, 29th day postoperatively. The manifestation of tumors in CT scan was observed and tumor volume was calculated simultaneously with formula V=1/2ab2 (a=the shortest diameter and b=the longest diameter).Each tumor was confirmed through pathology. Results:The implanting time of Group A and Group B were (9.47?2.85)min and (5.85?1.62)min, respectively, with significant difference between them. Besides, there was statistical difference of the achievement ratio between two groups, as it was 53.3% for Group A and 86.7% for Group B. No significant difference was found for the tumor growth between two groups. Conclusion:Modified implanting method for induction of the rabbit liver tumor model was superior to the classic implanting method.
