Detection of CRP in rat chronic periodontitis and atherosclerosis compound model
- VernacularTitle:血清C反应蛋白在大鼠慢性牙周炎合并动脉粥样硬化模型中的表达
- Author:
Jia NI
;
Yuanming ZHANG
;
Jun XU
;
Liangjun ZHONG
;
Fangchuan SHI
;
Xiaohuan ZHOU
- Publication Type:Journal Article
- Keywords:
chronic periodontitis;
atherosclerosis;
rat;
C-reactive protein
- From:
Basic & Clinical Medicine
2006;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To detect and analyse CRP level in rat chronic periodontitis and atherosclerosis compound model.Methods Sixty rats were randomly divided into four groups,15 in each group: Group A:control group;Group B:periodontitis group;Group C:atherosclerosis group;Group D:periodontitis and atherosclerosis group.Every group accepted the corresponding treatment.Pathological changes in periodontal tissue of experimental teeth and arterial vessels were observed.CRP level in serum was assayed by ELISA.Results Histopathological observation of periodontal tissue revealed: Obvious inflammation of periodontal tissue was observed in group B,D.Attachment loss levels in group B and D were higher than that of A,C groups(P
