An analysis of bone-biomaterial interface using transmission electron microscopy and in vivo hybridization
- VernacularTitle:骨与生物材料界面的透射电镜与体内杂交方法分析
- Author:
Feng XIN
;
Hui ZENG
;
Jiyun LI
;
Bo ZHANG
- Publication Type:Journal Article
- From:
Chinese Journal of Tissue Engineering Research
2007;0(08):-
- CountryChina
- Language:Chinese
-
Abstract:
The bioactive materials, such as biological glass, hydroxyl apatite, glass ceramics which contains the hydroxyl apatite and wollastonite, are possible to unify with the bone tissue together. However, many questions like whether the materials contact and unify directly with the bone, whether the speeds of unification have the differences, and whether materials themselves simultaneously have abilities to promote the bone formation are not clear and wait for the exposition. The researches have been made to observe the contact surface between biological material and bone, as well as the relationship among the apatite level and the bioactivity of materials through the transmission electron microscopy. In addition, in vivo hybridization has been used to discuss the mRNA expression and its influence in the cell around materials. The conclusion is that the bioactivity of glass ceramics is higher than that of hydroxyl apatite, with the easy unification with bone tissue.
