Role of protein kinase C in cell apoptosis
- VernacularTitle:蛋白激酶C在细胞及肿瘤细胞凋亡中的作用
- Author:
Guili SUN
;
Dapeng WANG
- Publication Type:Journal Article
- From:
Chinese Journal of Tissue Engineering Research
2007;0(07):-
- CountryChina
- Language:Chinese
-
Abstract:
Protein kinase C (PKC) is a serine/threonine kinase, which plays an important role in cell proliferation, differentiation and apoptosis. The activation of PKC has closely correlation to tumorigenesis, development and metastasis. Activation of PKC is one of key link in the cell signal transduction passway, which mediated cellular signals, participated expression of genes, and influenced cell cycles. Therefore, delivering drugs based on anti-cell information may provide a broaden prospect for anti-tumor therapy.
