Drug-resistance and Disinfectant-resistant Genes of Chlorhexidine-sulfadiazine-resistant Escherichia coli Isolates
- VernacularTitle:大肠埃希菌连续分离株耐药性与季胺类化合物耐药基因研究
- Author:
Wei WANG
;
Jianfeng MAO
;
Weizhen XU
- Publication Type:Journal Article
- Keywords:
Escherichia coli;
Drug-resistance;
Disinfectant-resistant genes
- From:
Chinese Journal of Nosocomiology
2006;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE To investigate the resistance and the disinfectant-resistant genes of chlorhexidine-sulfadiazine-resistant Escherichia coli isolates from hospitalized patients in the Lishui People's Hospital.METHODS Microdilute tests were performed to detect susceptibility to 19 kinds of antimicrobial agents in 60 E.coli strains,and the qacE△1 gene was detected by PCR.RESULTS The resistant rates to other antimicrobial agents arranged in 5.0-90.0%.The prevalence of ESBLs in isolates was 45.0%.qacE△1 Gene was 56.7%.CONCLUSIONS The 60 strains are multiple-drug-resistant.There are very high positive percentages of qacE△1 gene in E.coli isolates from the hospital.