Nosocomial Infections Caused by Coagulase Negative Staphylococcus and Drug-resistance
- VernacularTitle:凝固酶阴性葡萄球菌医院感染及体外耐药监测
- Author:
Mingju DONG
;
Li SHI
- Publication Type:Journal Article
- Keywords:
Coagulase negative staphylococcus(CNS);
Nosocomial infections;
Drug-resistance;
Monitoring
- From:
Chinese Journal of Nosocomiology
2006;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE To study drug-resistance status of nosocomial infections caused by coagulase negative staphylococcus(CNS)to offer scientific basis for reasonable usage of antibiotics.METHODS CNS were all identified by VITEK32 system.The drug suspectivity was tested by K-B method.The results were judged according to NCCLS/CLSI2004.RESULTS Among 258 strains of CNS,111 strains of Staphylococcus haemolyticus ranked the top,accounting for 43.0% and followed by 98 strains of S.epidermidis(38.0%).The isolating rate of meticillin-resistant coagulase-negative staphylococcus(MRCNS)was 51.9%(134/258).The drug-resistance rate of MRCNS was higher obviously than that of methicillin-susceptible coagulase-negative staphylococcus(MSCNS).CONCLUSIONS CNS has been one of the important pathogens of nosocomial infections.MRCNS with higher isolating rate showed multi-drug resistance.The glycopeptide antibiotics are the first choice to cure MRCNS infections.
