Genus Distribution and Drug Resistance of Invasive Fungal Infections
- VernacularTitle:深部真菌医院感染的菌群分布及耐药性分析
- Author:
Wenping WANG
;
Lei ZHU
- Publication Type:Journal Article
- Keywords:
Invasive fungus;
Nosocomial infections;
Genus distribution;
Drug resistance
- From:
Chinese Journal of Nosocomiology
2006;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE To study the prevalence,pathogenic characteristics and drug resistance of the invasive fungal infection to provide the reference for clinical treatment.METHODS The fungi were cultured and identified conventionally.The susceptibility test was performed by K-B disk diffusion methods.The data were analyzed by WHONET 5.3 software.RESULTS Among 232 strains of fungi,isolating rate of fungi from sputum was the highest,accounting for 74.1%.The following was urine,accounting for 17.2%.The most common organisms were Candida(96.6%)among which white Candida albicans accounted for 58.6%,following by C.tropicalis(13.8%),C.parapsilosis(10.3%),C.glablate(8.6%)and C.krusei(4.3%).Drug resistance to four commonly used antifungal drugs showed drug sensitivity to amphotericin B and itraconazole was higher,while that to fluconazole and flucytosine was lower.CONCLUSIONS Significant difference of drug resistance occurs among invasive fungus species.The cross resistance to azole antifungals is existing and has a raising tendency.
