Effect of Laparoscopic Repair of Inguinal Hernia on the Serum Levels of Cytokine IL-6,IL-10,and CRP in Children
- VernacularTitle:腹腔镜治疗腹股沟斜疝对小儿血CRP、IL-6、IL-10的影响
- Author:
Xiaolong ZHOU
;
Long LI
;
Xuanzhao WU
- Publication Type:Journal Article
- Keywords:
Laparoscopic surgery;
Open surgery;
IL-6;
IL-10;
C-reactive protein
- From:
Chinese Journal of Minimally Invasive Surgery
2001;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the changes of CRP,IL-6,and IL-10 levels after laparoscopic or open repair of inguinal hernia in children.Methods Fifty children with inguinal hernia were randomly assigned to laparoscopic repair or open surgery groups(25 in each).In the laparoscopic group(LS group),the hernia sac was closed by ligating the inner ring,while in the open surgery group(OS group),high ligation was performed.The peripheral blood samples of the two groups were collected one day before,immediately after,and one day after the operations.ELISA was used to detect the levels of CRP,IL-6,and IL-10.Results In both the groups,the levels of CRP,IL-6,and IL-10 were significantly increased immediately after the surgeries(LS Group:q=8.508,11.307,and 22.111,P0.05),while in the OS group,the levels remained significantly higher(q=3.845,10.599,and 11.379,P
