Antibiotic-resistant Genetical Marks of Integron and Transposon in Pseudomonas aeruginosa Strains Isolated in Two Hospitals
- VernacularTitle:两所医院铜绿假单胞菌连续分离株耐药性与整合子、转座子遗传标记研究
- Author:
Jiaping WANG
;
Lixia ZHAO
;
Sujian WANG
;
Xiaomei ZHANG
;
Zuhuang MI
- Publication Type:Journal Article
- Keywords:
Pseudomonas aeruginosa;
Integron;
Transposon
- From:
Chinese Journal of Nosocomiology
1994;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE To investigate the antibiotic resistance and the genetical marks in Pseudomonas aeruginosa(PAE) strains in two hospitals of Jiangsu and Zhejiang.METHODS The drug-resistance in PAE strains was detected with K-B test,four kinds of genetical marks of integron and transposon(qacE△1-sul1,mer,tnpA and tnpU) were detected by PCR.RESULTS The strains were only sensitive to cefoperazone/sulbactam,imipenem,meropenem and amikacin.There was a high resistance rate to ?-lactamases,ciprofloxacin,and sulfamethoxazole.Genes of qacE△1-sul1(48.6%,45.0%) and merA(11.4%,5.0%) were detected from PAE strains in the two hospitals.There were no tnpA and tnpU too.CONCLUSIONS Multiple-drug-resistance in Pseudomonas aeruginosa(PAE) strains is caused mainly by qacE△1-sul1 and merA.
