Antibiotic Resistance Genes Detection in Meticillin-resistant Coagulase Negative Staphylococcus
- VernacularTitle:耐甲氧西林凝固酶阴性葡萄球菌耐药基因检测
- Author:
Min LIU
;
Li SHI
;
Mingju DONG
;
Tao SONG
;
Guangcheng SUN
- Publication Type:Journal Article
- Keywords:
Staphylococcus;
Antibiotic-resistant genes;
Meticillin-resistant staphylococcus
- From:
Chinese Journal of Nosocomiology
1994;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE To study the epidemiology of the drug-resistant genes in meticillin-resistant coagulase negative staphylococcus(MRCNS).METHODS mecA,aac(6′)/aph(2″) and aph(3′)-Ⅲgenes of aminoglycoside-modifying enzyme(AME) and ermA/B/C genes of erythromycin methyltransferase were detected by polymerase chain reaction(PCR) from 40 MRCNS strains.RESULTS Thirty-nine strains carried mecA gene,32 strains with aac(6′)/aph(2″) gene,15 strains with aph(3′)-Ⅲ gene,30 strains with ermA/B/C gene and 2 strains with tetM gene in 40 MRCNS strains.CONCLUSIONS About 65% MRCNS strains carry mecA,aac(6′)/aph(2″),/aph(3′)-Ⅲ and ermA/B/C genes at the same time.
