Resistance to ?-Lactam Antibiotics and Meropenem of 239 Non-ESBLs-producing Escherichia coli Isolates
- VernacularTitle:239株非产超广谱?-内酰胺酶大肠埃希菌对?-内酰胺类抗菌药物及美罗培南的耐药性检测
- Author:
Hui WANG
;
Zizhong XIONG
;
Hongxia CAO
;
Yanyan WEI
;
Zhongxin WANG
- Publication Type:Journal Article
- Keywords:
Escherichia coli;
Extended-spectrum ?-lactamases;
Resistance
- From:
Chinese Journal of Nosocomiology
1994;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE To investigate the resistance to ?-lactam antibiotics and meropenem of non-ESBLs-producing Escherichia coli isolates.METHODS Non-ESBLs producers of E.coli isolates were detected by CLSI phenotypic confirmatory test,and susceptibility of these isolates to ?-lactam antibiotics and meropenem was tested by agar dilution method.RESULTS The resistance rate of these isolates to ampicillin,cefazolin and cefoxime was more than 60% and that to cefoperazone-sulbactam,cefmetazole and cefepime was 19.2%,23.8% and 31.8%,respectively,but most were susceptible to cefotaxime,ceftazidime,and meropenem.CONCLUSIONS The most isolates of non-ESBLs-producing E.coli are resistant to ampicillin and to the first and second generation cephalosporins,but they are susceptible to meropenem and the third generation cephalosporins.
