IL-16 in Senile Chronic Obstructive Pulmanary Disease (COPD) and Its Clinical Significance
- VernacularTitle:老年慢性阻塞性肺疾病气道炎症痰白介素-16检测的研究
- Author:
Tian TIAN
- Publication Type:Journal Article
- Keywords:
COPD;
Cytokine;
IL-16
- From:
Chinese Journal of Nosocomiology
1994;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE To investigate the role of IL-16 in the process of airway inflammation of chronic obstructive pulmanory disease(COPD) patients.METHODS The sputum of 60 COPD elderly was collected in the period of exacerbation and alleviation.Serum level of IL-16 was tested using ELISA.RESULTS IL-16 level was higher in severe [(4240.7?296.36,1737.59?367.81)pg/ml] and moderate [(3125.87?286.35,1564.34?478.99)pg/ml] COPD patients in exacerbation and alleviation period than in mild patients(173.75?31.26,129.27?23.89)pg/ml and IL-16 level decreased after effective therapy.CONCLUSIONS IL-16 participates in the procedure of airway inflammation.Surveillence of dynamic variation of IL-16 can reflect the severity of airway inflammation,but it can not offer more diagnostic value.
