Bone morphogenetic protein and bone defect repair
- VernacularTitle:骨形态发生蛋白与骨缺损的修复
- Author:
Zhiqiang QU
;
Mushun HE
;
Yuedong ZENG
;
Yu DAI
- Publication Type:Journal Article
- From:
Chinese Journal of Tissue Engineering Research
2007;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
Physical continuity of bone is damaged following bone defects. The use of exogenous bone morphogenetic protein (BMP) treatment depends on appropriate carrier, which releases exogenous BMP and other growth factor into the bone defect site, inducing new bone formation and achieving therapeutic purposes. There are many carrier materials for BMP, including inorganic material, synthetic polymers, biological material, and composites of these three materials. But all have some deficiencies. So many researchers have optimized them by combined, physical and chemical methods to improve the bone inductive activity. BMP, which is released from carrier or local gene, can repair bone defect effectively, affording a new way for bone defect repairing.
