Application status of allogenic blood transfusion in orthopedics treatment
- VernacularTitle:异体血细胞移植在骨科治疗中的应用现状
- Author:
Shilong LIU
;
Wali LI
;
Bo SUN
- Publication Type:Journal Article
- From:
Chinese Journal of Tissue Engineering Research
2008;0(53):-
- CountryChina
- Language:Chinese
-
Abstract:
Tissue engineering may allow obtaining patient’s own cells, seeding them on biodegradable scaffolds, thus achieving formation of a particular tissue or organs, such as bone, cartilage, muscle, or heart. These tissues or organs can be used to repair tissue or organs defects caused by disease or trauma. Many animal studies have demonstrated the efficacy of using bone marrow mesenchymal stem cells in treatment of diseases such as nervous system diseases, liver disease, respiratory diseases and kidney disease. The main ways of the stem cells therapy are local implantation and systemic transplantation of bone marrow mesenchymal stem cells, and the effect of such treatments is notable. The use of gene-modified stem cells in gene therapy is an fantastic option due to theoretical advantage of stem cells compared to somatic cells with respect to higher proliferative capacity. Bone marrow mesenchymal stem cells can deliver genes and proteins into organs or tissues with specific need for gene therapy.
