Analysis of the NAT-HBV/HCV results of single ALT(+) blood donors
- VernacularTitle:无偿献血者ALT报废域值与NAT-HBV/HCV检测结果分析
- Author:
Wentao ZOU
;
Tiebin WANG
;
Ziyi HE
- Publication Type:Journal Article
- Keywords:
Blood donor;
ALT;
NAT-HBV/HCV
- From:
Chinese Journal of Blood Transfusion
2008;0(12):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the NAT(nucleic acid amplification technique)-HBV/HCV results among single ALT(+)blood donors,in order to provide theoretical basis of optimizing strategy for blood screening.Methods A total of 28 800 samples,from December 2006 to December 2007,were studied retrospectively.ALT was tested by rate method.HBV-DNA and HCV-RNA in single ALT(+) samples were detected via NAT-HBV/HCV.The relationship between positive ALT values and ELSIA-HBV/HCV OD values was analyzed.Results A total of 2 516 ALT(+) cases were found in 28 800 samples.Of these ALT(+)cases,8 positive cases were found via NAT-HBV/HCV,including 5 HBV-DNA(+) and 3 HCV-RNA(+) cases.The positive rates of NAT-HBV/HCV for the donors with ALT values ≤80 U/L were significant lower than those with ALT values≥81 U/L(P
