Biological function of heme oxygenase in its role in liver transplantation
- VernacularTitle:血红素加氧酶的生物学功能及其在肝移植中的作用研究进展
- Author:
Jing DING
;
Jiyu LI
- Publication Type:Journal Article
- Keywords:
Heme oxygenase;
Liver transplantation;
Ischemia-reperfusion injury;
Rejection reaction
- From:
Journal of Medical Postgraduates
2003;0(12):-
- CountryChina
- Language:Chinese
-
Abstract:
Heme oxygenase(HO) is a rate-limiting enzyme that catalyzes heme degradation.It catabolizes heme into 3 products: carbon monoxide(CO),free iron and bilirubin,which play an important role in keeping the steady state of the organism.In recent years,some studies show that the promotion of HO-1 expression can reduce ischemia-reperfusion injury of an organ transplant and regulate the transplantation immunological rejection.It has an important application prospect in liver transplantation.
