An experimental study on the expression of apoptosis conducted by nuclear factor-?B in benign and malignant pancreatic diseases
- VernacularTitle:核转录因子-?B介导的细胞凋亡在良恶性胰腺组织表达的实验研究
- Author:
Guowei ZHANG
;
Jie ZHOU
;
Caixian LIAO
- Publication Type:Journal Article
- Keywords:
Nuclear factor-?B;
Pancreatic cancer;
Chronic pancreatitis;
Apoptosis
- From:
Journal of Medical Postgraduates
2003;0(12):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:By measuring the expression of nuclear factor of ?B(NF-?B) and apoptosis in the tissue of benign and malignant pancreatic diseases.Methods:The expression of NF-?B factor was measured by immunohistochemical method to measure.The expression of apoptosis for cells was determined by TUNEL method.Results: When measuring the expression of NF-?B p65 protein in the tissue,we found firstly,in the tissue of pancreatic cancer,NF-?B p65 protein was located in the nucleolus and cytoplasm,the number of positive cell was obviously more than that in the control group(P
