Progress on Escherichia coli AcrAB-TolC Multidrug Efflux Pump and Its Regulation
- VernacularTitle:大肠杆菌的AcrAB-TolC多药外排泵及其调控研究进展
- Author:
Jinhui HOU
- Publication Type:Journal Article
- Keywords:
Multidrug resistance, Escherichia coli, AcrAB-TolC efflux pump, Gene regulation
- From:
Microbiology
2008;0(12):-
- CountryChina
- Language:Chinese
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Abstract:
Multidrug efflux pump is the main reason for bacterial multidrug resistance, and it’s a chal- lenge for the treatment of infectious diseases. Analysis of multidrug efflux pump offers us the mecha- nism and treatment ideas of bacterial multidrug resistance. New advances have been made in the study of Escherichia coli AcrAB-TolC efflux pump structure and its regulation, which provides data for the multidrug resistance research in pathogenic bacterium. Progress in this area is reviewed here.
