Bacterial Drug-Resistance in Intensive Care Unit: An Initial Analysis
- VernacularTitle:重症监护病房病原菌耐药性分析
- Author:
Zhengfu JIA
- Publication Type:Journal Article
- Keywords:
Intensive care unit;
Bacterium;
Drug-resistance
- From:
Chinese Journal of Nosocomiology
2006;0(12):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE To contrast drug-resistance of pathogenes isolated from the intensive care unit(ICU) with that from the non-ICU and understand pathogens distribution and drug-resistance characteristic in ICU in order to provide the evidence for clinical experiential theatment.METHODS The WHONET software was used to analyze the antibiotic resistant rates of 338 strains of pathogens isolated from specimens in ICU from Jan 2001 to Oct 2007.RESULTS The sputum and swallow swab specimen rated the top one(66.6%).The following was blood sample,accounted for 13.6%.The pathogens of the top three of isolating rate were the 66 strains of Klebsiella pneumoniae(19.5%),57 strains of Staphyloccus aureus(16.9%) and 51 strains of Pseudomonas aeruginosa(15.1%).Isolating rate of meticillin-resistant Staphylococcus aureus accounted for 93.8%.Except for imipenem,cefepime and tetracycline,drug-resistance of K.pneumoniae to common antibiotics in ICU was all higher than that in non-ICU.The drug-resistance of P.aeruginosa to imipenem in ICU arrived at 72.2% while that in the non-ICU was 17.9%.CONCLUSIONS ICU is one of the highly susceptible departments where the drug-resistance of the pathogens is generally higher than that in the non-ICU and possesses the particularity other than the non-ICU.
