Safety and Efficacy of an Aortic Arch Stent Graft with Window-Shaped Fenestration for Supra-Aortic Arch Vessels: an Experimental Study in Swine.
- Author:
Jong Ha PARK
1
;
Han Cheol LEE
;
Jeong Cheon CHOE
;
Sang Pil KIM
;
Tae Sik PARK
;
Jinhee AHN
;
Jin Sup PARK
;
Hye Won LEE
;
Jun Hyok OH
;
Jung Hyun CHOI
;
Kwang Soo CHA
Author Information
- Publication Type:Original Article
- Keywords: Stents; Aneurysm, thoracic aortic; Aortic diseases; Animal experimentation
- MeSH: Animal Experimentation; Aorta, Thoracic*; Aortic Aneurysm, Thoracic; Aortic Diseases; Autopsy; Blood Vessel Prosthesis*; Carotid Arteries; Catheters; Congenital Abnormalities; Endoleak; Iliac Artery; Pathology; Stents*; Swine*; Transplants
- From:Korean Circulation Journal 2017;47(2):215-221
- CountryRepublic of Korea
- Language:English
- Abstract: BACKGROUND AND OBJECTIVES: Thoracic endovascular aortic repair exhibits limitations in cases where the aortic pathology involves the aortic arch. We had already developed a fenestrated aortic stent graft (FASG) with a preloaded catheter for aortic pathology involving the aortic arch. FASG was suitable for elective cases. MATERIALS AND METHODS: An aortic arch stent graft with a window-shaped fenestration (FASG-W) for supra-aortic arch vessels is suitable for emergent cases. This study aims to test a FASG-W for supra-aortic arch vessels and to perform a preclinical study in swine to evaluate the safety and efficacy of this device. Six FASG-Ws with 1 preloaded catheter were advanced through the iliac artery in 6 swine. The presence of endoleak and the patency and deformity of the grafts were examined with computed tomography (CT) at 4 weeks postoperatively. A postmortem examination was performed at 8 weeks. The mean procedure time for FASG-W was 27.15±4.02 minutes. The mean time for the selection of the right carotid artery was 5.72±0.72 minutes. RESULTS: Major adverse events were not observed in any of the 6 pigs who survived for 8 weeks. For the FASG-W, no endoleaks, no disconnection, and no occlusion of the stent grafts were observed in the CT findings or the postmortem gross findings. CONCLUSION: The procedure with the FASG-W was able to be performed safely in a relatively short procedure time and involved an easy technique. The FASG-W was found to be safe and convenient for use in this preclinical study of swine.
