Effects of glucocorticoid on the expression of CD80 and CD4~+CD25~+T cells in peripheral blood lymphocyte of patients with multiple sclerosis
- VernacularTitle:糖皮质激素对多发性硬化患者外周血淋巴细胞CD80和CD4~+CD25~+T细胞表达的影响
- Author:
Yulan TANG
;
Peiying QIN
;
Haihong LI
- Publication Type:Journal Article
- Keywords:
multiple sclerosis;
CD80;
CD4+CD25+T cells;
glucocorticoid
- From:
Journal of Clinical Neurology
1997;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the effects of glucocorticoid(GC) on the expression of CD80 and CD4+CD25+T cells in peripheral blood lymphocyte of patients with multiple sclerosis (MS). Methods With flow cytometer,the positive rates of CD80 and CD4+CD25+T cells in peripheral blood lymphocyte were detected in 21 acute MS patients pre and post treatment separately,and compared with the nomal control group.The secols of Expanded Disablility Status Scale(EDSS) were compared pre and post treatment in MS patients.Results The positive rate of CD80[(5.031?1.782)%]in the MS patients pre treatment was obviously less than that in control group's [(6.436?2.035)%](P
