Sub-clinical inflammation and insulin resistance in patients with cerebral infarction
- VernacularTitle:脑梗死患者的亚临床炎症及胰岛素抵抗
- Author:
Shiying LI
;
Bing YAN
;
Hechuan ZANG
- Publication Type:Journal Article
- Keywords:
cerebral infarction;
inflammation;
insulin resistance;
C-reactive protein;
interleukin-6
- From:
Journal of Clinical Neurology
1997;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the sub-clinical inflammation and insulin resistance (IR) in patients with cerebral infarction(CI). Methods The levels of serum C-reactive protein (CRP),interleukin-6 (IL-6),fasting insulin (Fins),fasting plasma glucose (FPG),blood lipids and blood pressure were measured in 114 patients with CI (CI group). The insulin sensitivity index (ISI) was observed and the correlation between ISI and indexes of inflammation were analysed. The results were compared with 70 patients without CI(control group). Results (1) The levels of serum CRP [(2.73?0.87) mg/L]and IL-6[(0.14?0.03) ng/ml] in CI group were significantly higher and ISI(-4.31?0.53) was significantly lower compared with control group[CRP(1.63?0.93) mg/L,IL-6(0.12?0.03) ng/ml,ISI(-3.92?0.43)] ( all P8.2 mg/L was significantly lower than that in the patients with the CRP≤8.2 mg/L (-4.18?0.54)(P
