Relationship between the level of serum homocysteinaemia and carotid artery atherosclerosis and its change after intervention therapy
- VernacularTitle:血清同型半胱氨酸水平与颈动脉粥样硬化的关系及干预后的变化
- Author:
Xiaomei TANG
;
Huiping ZHU
;
Li LIU
- Publication Type:Journal Article
- Keywords:
carotid artery atherosclerosis;
homocysteine;
folic acid;
Vitamin B12
- From:
Journal of Clinical Neurology
1997;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the relationship between the level of serum homocysteinaemia(Hcy) and the carotid artery atherosclerosis(CAA),and its change after intervention therapy with folate acid and VitaminB12 (VitB12). Methods The levels of serum Hcy,folate acid and VitB12 were measured in 169 patients with cerebral infarction(CI group) and 110 normal controls(NC group). The condition of carotid arteries was checked by color dopper flow image in CI group. The relationship between the level of serum Hcy and folate acid,VitB12 and CAA condition were analysed. The change of serum Hcy level was observed after intervention treatment of folate acid and VitB12 for 4 weeks in CI patients with hyperhomocysteinaemia.Results Compared with the NC group,the level of serum Hcy was significant higher in CI group(P
