Biocompatibility-associated index alterations in vascular implantation
- VernacularTitle:血管植入物置入过程中生物相容性反应的相关指标变化
- Author:
Xiaomei ZHANG
- Publication Type:Journal Article
- From:
Chinese Journal of Tissue Engineering Research
2007;0(52):-
- CountryChina
- Language:Chinese
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Abstract:
Injury of blood vessel and subsequent repairing reactions to injury during vascular implant implantation can induce local and systematical inflammatory reactions,platelet and inflammatory cell aggregation,release of inflammation transmitter,chemotactic factor and tumor necrosis factor,which promotes vascular smooth muscle cell migration and proliferation,ultimately restenosis.Inflammatory reactions following implantation is highly correlated with intravascular restenosis.Well understanding of inflammatory factor features,monitoring of inflammatory factor index alterations,and taking some measures to increase histocompatibility can reduce inflammatory reaction intensity and duration.In addition,drug-eluting stent and skilled implanting technique can reduce incidence of inflammatory reactions.