Clinical Features and Outcomes of Meconium Intestinal Obstruction in Preterm Infants.
- Author:
Geum Chae Won YI
1
;
Kyung Ji KANG
;
Eun Ha KIM
;
Chun Soo KIM
;
Sang Lak LEE
Author Information
1. Department of Pediatrics, Keimyung University School of Medicine, Daegu, Korea. cskim@dsmc.or.kr
- Publication Type:Original Article
- Keywords:
Meconium;
Intestinal obstruction;
Premature infant
- MeSH:
Colon;
Diatrizoate Meglumine;
Enema;
Enteral Nutrition;
Humans;
Hypertension;
Infant;
Infant, Newborn;
Infant, Premature;
Intensive Care, Neonatal;
Intestinal Obstruction;
Length of Stay;
Magnesium Sulfate;
Meconium;
Medical Records;
Parturition;
Retrospective Studies
- From:Korean Journal of Perinatology
2012;23(4):242-250
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
PURPOSE: This study was undertaken to investigate the clinical features and outcomes of meconium intestinal obstruction (MIO) in preterm infants. METHODS: A retrospective analysis of medical records and radiologic images was conducted in a neonatal intensive care unit over a 3-year period (2009-2011). In addition, birth year- and gestational age-matched babies were selected by random sampling with twice the number as the control group. RESULTS: There were 43 infants with MIO who were appropriate as subjects. In perinatal factors, a maternal history of hypertension and the use of magnesium sulfate were more frequent in patients with MIO, but not significant. Feeding intolerance was more common in the MIO group than the control (86% vs. 24.4%; P<0.001). The frequency of gastrografin enema was once in all but one of the patients, and the microcolon was detected in 7 cases (16.3%. Radiographic change after enema was seen earlier than clinical improvement (P<0.05).The patients with MIO took longer to achieve full enteral feeding, and had a more prolonged hospital stay (P<0.001). CONCLUSION: Feeding intolerance in preterm infants may be an early clinical finding of MIO. Meconium obstruction causes a delay of full enteral feeding and extension of hospital stay.
