Correlation between myocardial function and plasma endothelin in patients with coronary heart disease
- VernacularTitle:冠心病患者血浆内皮素水平与心脏收缩功能的研究
- Author:
Jiming XIAO
;
Jun XU
;
Ruihua CHEN
- Publication Type:Journal Article
- Keywords:
Coronary heart disease;
Endothelin;
Heart function
- From:
Journal of Medical Postgraduates
2003;0(11):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To investigate the dynamic changes in the content of endothelin(ET) in the plasma of coronary heart disease(CHD) patients and the relationship between myocardial function and ET.Methods: The plasma ET levels of 62 CHD patients were measured by immunoradiometric assay(IRMA) at 12 h,24 h,48 h,96 h and 7 d after the attack of CHD.The left ventricular ejection fraction(LVEF) was detected by echocardiography and the cardiac function was assessed according to the NYHA classification criteria.Results: The plasma ET level was significantly higher in the CHD patients than in the healthy controls(P
