Impact of obesity on women with polycystic ovary syndrome
- VernacularTitle:肥胖对多囊卵巢综合征患者生殖内分泌功能的影响
- Author:
Min HU
;
Wei LI
;
Xiaoke WU
- Publication Type:Journal Article
- Keywords:
Obesity;
Polycystic ovary syndrome;
Reproduction
- From:
Journal of Medical Postgraduates
2003;0(11):-
- CountryChina
- Language:Chinese
-
Abstract:
Polycystic ovary syndrome(PCOS),one of the most common causes of anovulation-induced infertility,is largely dependent on the influence of obesity and metabolic alterations,including an insulinresistant state and the metabolic syndrome,which consistently affect most women with PCOS.The clinical phenotype and the pathophysiological interact between obesity and PCOS have also been changed obviously in these paitients.Obesity has profound effects on the reproductive function of PCOS women and,particularly the abdominal phenotype,may add to the chances of androgen excess,PCOS,insulin resistance and hyperinsulinaemia.Obesity plays an important role in the pathogenesis of PCOS and obesity-associated metabolic alterations have a long-term impact on the patients' health.