Progress in the study of leptin and childhood obesity
- VernacularTitle:瘦素与儿童肥胖研究进展
- Author:
Yang MENG
;
Junjun WANG
- Publication Type:Journal Article
- Keywords:
Leptin;
Childhood obesity;
Leptin receptor
- From:
Journal of Medical Postgraduates
2003;0(11):-
- CountryChina
- Language:Chinese
-
Abstract:
Leptin,a proteohormone primarily made by adipocytes,directly interacts with the hypothalamus for energy balance regulation.It plays an important role in the morbility of obesity.The soluble leptin receptor(sOb-R) is one of the leptin receptor isoforms.The examination of the sOb-R concentration is valuable because of its function in the regulation of leptin concentration.Leptin shows a great potential as a childhood obesity biomarker,and its concentration could be used in assessing the responsiveness of obese children to intervention programs.
