Cryosurgery for Middle and Late Stage Central Lung Cancer with Fiber Optic Bronchoscopy
- VernacularTitle:经纤维支气管镜冷冻治疗中、晚期中心型肺癌致气道梗阻的疗效
- Author:
Bin SHI
;
Deruo LIU
;
Yongqing GUO
- Publication Type:Journal Article
- Keywords:
Lung cancer;
Fiber optic bronchoscope;
Cryosurgery
- From:
Chinese Journal of Minimally Invasive Surgery
2005;0(11):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the effectiveness of cryosurgery by using fiber optic bronchoscope for the treatment of middle or late stage central lung cancer.Methods Cryosurgery was performed on 31 patients with middle or late stage central lung cancer,who could not received open surgery,with liquid CO2 by using fiber optic bronchoscope.The effectiveness was monitored.Via the bronchoscope,a cryo-probe was inserted to the center or margin of the tumor.The cryotherapy was persisted for 30 to 120 seconds at-50 to-70 ℃.And then,the tumor was removed before the ice-ball on the point of the probe thawed.The procedure was repeated for several times till the airway was reopened.Results After 1 to 6 times therapies(2.5 times on average),the improve rates of cough,hemoptysis,dyspnea,and chest pain were 74%(23/31),87%(27/31),87%(27/31),and 58%(18/31),respectively.The rates of "markedly effective"and "effective" were 61%(19/31)and 39%(12/31)respectively.The pulmonary function of the patients was also improved:the FEV1 rose from(1.21?0.22)L to(1.72?0.35)L(t=21.843,P=0.001),and the FVC was increased from(1.86?0.31)L to(2.26?0.43)L(t=33.703,P=0.001).Conclusions Cryosurgery by using a fiber optic bronchoscope is an effective and minimally invasive method to reopen the airway,control the obstructive pneumonia,and improve dyspnea and hemoptysis.
