Two Cases of Congenital Cytomegalovirus Infection with Pulmonary Hypertension.
- Author:
Ah Young KIM
1
;
Yong Seok KIM
;
Kyung Hee PARK
;
Shin Yun BYUN
Author Information
1. Department of Pediatrics, Pusan National University School of Medicine, Yangsan, Korea. byun410@hanmail.net
- Publication Type:Case Report
- Keywords:
Cytomegalovirus;
Pulmonary hypertension
- MeSH:
Cholestasis;
Cytomegalovirus;
Cytomegalovirus Infections;
Fetal Growth Retardation;
Ganciclovir;
Hearing Loss;
Hypertension, Pulmonary;
Intellectual Disability;
Thrombocytopenia;
Ventilators, Mechanical
- From:Korean Journal of Perinatology
2012;23(4):273-279
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Cytomegalovirus (CMV) is the most common cause of intrauterine infection. 90% of congenital CMV infection being asymptomatic, only 5% of CMV infections are presented with severe symptoms: intrauterine growth retardation, petechia, hepatosplenomegaly, thrombocytopenia, hearing loss and mental retardation. We experienced two cases of symptomatic congenital CMV infection with persistent pulmonary hypertension in NICU who presented intrauterine growth retardation, petechia, cholestasis, hepatosplenomegaly, and thrombocytopenia. Persistent pulmonary hypertension improved after ventilator care, and hearing loss also improved after ganciclovir treatment for 6 weeks.
