Potential value of bone marrow mesenchymal stem cells in the treatment of idiopathic pulmonary fibrosis
- VernacularTitle:骨髓间充质干细胞在特发性肺纤维化治疗中的潜在应用价值
- Author:
Jianyong ZOU
;
Honghe LUO
;
Zhenguang CHEN
- Publication Type:Journal Article
- From:
Chinese Journal of Tissue Engineering Research
2007;0(47):-
- CountryChina
- Language:Chinese
-
Abstract:
Idiopathic pulmonary fibrosis is a diffuse pulmonary fibrosis disease.At present,there are still no effective treatments for this disease,so the prognosis is poor and 5 years of survival rates was only 20%.Bone marrow mesenchymal stem cells(BMSCs),derived from bone marrow,is a kind of multipotent stem cells,which have potential to differentiate into many lineages of cells.So,they are considered to have great latent values in clinic.In recent years,related studies had found that BMSCs might participate in the repair of the lung injury,even they can reverse the pathological progress in idiopathic pulmonary fibrosis.But the mechanism is still unclear and needs more research to elucidate.
