Relationship Between Variation and Distribution of Differential Gene Sites of Hepatitis B Virus and Enzymatic Activity of Liver Function
- VernacularTitle:乙型肝炎病毒不同位点变异及其分布与肝功能酶活力的表达关系
- Author:
Ranfeng CHEN
;
Guojun CHEN
;
Qirong CHEN
;
Zhiyong HUANG
;
Xiaodong JIN
;
Yong YANG
- Publication Type:Journal Article
- Keywords:
Hepatitis B virus;
YMDD variation;
A1762T variation;
G1896A variation;
Enzymatic activity;
Distribution
- From:
Chinese Journal of Nosocomiology
2005;0(11):-
- CountryChina
- Language:Chinese
-
Abstract:
0.05).CONCLUSIONS G1896A Variation principally distributes in HBeAg(-) group that expressed low level HBV DNA.A1762T Variation and HBeAg(+) haven′t obvious correlation.YMDD variation principally distributes in HBeAg(+) group that expressed high lever HBV DNA.YMDD variation initiates acute damage of liver cell.The variation of G1896A or A1762T may contribute to progressive damage of chronic liver disease.