Study on methods for detection of multidrug-resistance genes MDR1 C3435T and G2677T/A single nucleotide polymorphisms
- VernacularTitle:多药耐药基因C3435T与G2677T/A单核苷酸多态性检测方法的探讨
- Author:
Jing FU
;
Yirong YANG
;
Xiaodong PAN
;
Jianjian ZHENG
;
Bicheng CHEN
- Publication Type:Journal Article
- Keywords:
multidrug resistance-1;
single nucleotide polymorphism;
polymerase chain reaction;
DNA sequencing
- From:
Chinese Journal of Clinical Laboratory Science
2006;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
0.05).The optimal combination was PCR-CTPP for MDR1 C3435T and PCR-SSP for G2677T/A.Conclusions PCR-CTPP and PCR-SSP are simple,accurate,rapid and economical methods for detection of SNP of MDR1 C3435T and G2677T/A,and can be applied in clinical research.