Regulation of TFPI-2 gene expression and its role in diseases
- VernacularTitle:TFPI-2基因的表达调控及其在疾病中的作用
- Author:
Qin ZHANG
;
Hong JIN
- Publication Type:Journal Article
- Keywords:
tissue factor pathway inhibitor-2;
tissue factor pathway inhibitor-2 gene;
gene expression adjusting;
artherosclerosis;
tumor
- From:
Basic & Clinical Medicine
2006;0(11):-
- CountryChina
- Language:Chinese
-
Abstract:
Tissue factor pathway inhibitor-2(TFPI-2) is a matrix-associated Kunitz-type serine proteinase inhibitor,and is considered to play an important role in some pathophysiological processes,including artherosclerosis,tumor metastasis and angiogenesis.Extracellular signals can regulate TFPI-2 gene expression through modulating promoter or signaling pathway or other factors.The mechanism,more over,has become one of the focus in recent years.
