Progress in the effects of CCN1 on cardiovascular system
- VernacularTitle:基质信号蛋白CCN1心血管作用研究进展
- Author:
Yang YU
;
Lan HUANG
- Publication Type:Journal Article
- Keywords:
CYR61;
CCN1;
cardiovascular
- From:
Basic & Clinical Medicine
2006;0(11):-
- CountryChina
- Language:Chinese
-
Abstract:
CCN1 is a novel extracellular matrix-associated signaling protein which possesses 381 amino-acid residues to compose 4 distinct structural modules with 38 conserved cysteine residues.This protein has a variety of properties in cardiovascular system,affecting the cellular behaviors such as differentiation,proliferation and migration of vascular endothelial cells,smooth muscle cells and cardiac myocytes,that suggested an essential roles of CCN1 in angiogensis,vascular injury,cardiac development and myocardial infarction.
