BKCa and atherogenesis
- VernacularTitle:大电导钙激活钾通道与动脉粥样硬化
- Author:
Xiangang MO
;
Xinglin LUO
- Publication Type:Journal Article
- Keywords:
big conductance Ca~(2+)-activated K+ channel;
atherosclerosis
- From:
Basic & Clinical Medicine
2006;0(11):-
- CountryChina
- Language:Chinese
-
Abstract:
Atherosclerosis is a kind of complex progressive inflammation.Exposure to atherogenic risk factors,particularly OxLDL,induces the activity of BKCa in endothelial cell,monocyte/macrophage(M?),vascular smooth muscle cell,platelet and other cells to activate,which precipitates dysfunction of the cells and therefore contributes to the development of atherosclerosis.This article briefly reviews the reseach progress in BKCa participating in the development of atherosclerosis.
