Genetics about idiopathic scoliosis
- VernacularTitle:特发性脊柱侧凸的遗传学研究
- Author:
Zhizhou YANG
;
Suxi GU
;
Ming LI
- Publication Type:Journal Article
- From:
Chinese Journal of Tissue Engineering Research
2007;0(46):-
- CountryChina
- Language:Chinese
-
Abstract:
Adolescent idiopathic scoliosis has a high incidence in orthopedics,researches about its etiology begins early.However,it is still unclear until now.Idiopathic scoliosis trends to a familial aggregation,and its inheritance is diverse,which suggests idiopathic scoliosis can be the result of the interaction of many factors and major genes.It is reported that the inheritance mode of idiopathic scoliosis includes autosomal dominant inheritance,X-linkage dominant inheritance and polygenic inheritance.With the consummate of genome genetic map and the development of genetic technology at recent years,scholars have gained much advancement through the researches in gene screening,candidate gene,gene mutation and animal model.Further study should focus on the accurate site of related genes.
