Changes in coagulation system and cytokines following intravascular stenting
- VernacularTitle:脑血管支架置入后凝血系统和细胞因子的变化
- Author:
Zhipeng LI
;
Pengfei WU
;
Zhitao JING
;
Yunjie WANG
- Publication Type:Journal Article
- From:
Chinese Journal of Tissue Engineering Research
2007;0(44):-
- CountryChina
- Language:Chinese
-
Abstract:
Intravascular stent as a foreign body exhibits obvious reaction following implantation,such as activation of coagulation system and elevation of serum C-reactive protein,inflammatory marker.After platelet is activated,P-selectin binds to the glycoprotein ligand 1 expressed on leukocyte,and forms congeries on the leukocyte.In addition,interleukin-1?,interleukin-6 and tumor necrosis factor-? are greatly secreted.The two factors are main reasons for restenosis following stent implantation.Studies on spiral CT angiography and transcranial Doppler sonography are important.
